PEDIATRIC MCQS: HEPATOLOGY

Interesting Facts about Hepatitis A, B, and C in MCQS FORM
1. A 10-month-old boy is being seen for reported hepatitis A exposure. Appropriate therapy at this time would include?
2. An 11-year-old boy is being seen for reported hepatitis A exposure. Appropriate therapy at this time would include?
3. Which of the following neonates should receive hepatitis B immune globulin within 12 hours after birth?
and many more-------------------------------------
PEDIATRIC MCQS: HEPATOLOGY

Quiz

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1. A 10-month-old boy is being seen for reported hepatitis A exposure. The exposure is thought to be from contaminated strawberries that his family purchased. He has not received any hepatitis A vaccination. He is currently asymptomatic. All of his vaccinations are up-to-date. Exposure is estimated to have occurred less than 2 weeks ago. Appropriate therapy at this time would include:
   1.   Ribavirin
   2.   Alpha interferon
   3.   Hepatitis A vaccination
   4.   Hepatitis B vaccination
   5.   Intramuscular immune globulin
2. An 11-year-old boy is being seen for reported hepatitis A exposure. The exposure is from contaminated strawberries that his family purchased at a local market. He has not received any hepatitis A vaccination. He is currently asymptomatic. All of his other vaccinations are up-to-date. Exposure is estimated to have occurred less than 2 weeks ago. Appropriate therapy at this time would include:
   1.   Ribavirin
   2.   Alpha interferon
   3.   Hepatitis A vaccination
   4.   Hepatitis B vaccination
   5.   Intramuscular immune globulin
3. A 13-year-old unvaccinated homeless youth seeks evaluation approximately 3 weeks after exposure to hepatitis B from needle sharing with a known carrier. In addition to testing for other infectious diseases contracted by needle sharing, the following are the most likely laboratory findings indicating a hepatitis B infection if labs were taken the day of the visit:
   1.   HBV DNA negative, HBV core protein IgM negative, HBsAg negative
   2.   HBV DNA positive, HBV core protein IgM positive, HBsAg positive
   3.   HBV DNA positive, HBV core protein IgM positive, HBsAg negative
   4.   HBV DNA positive, HBV core protein IgM negative, HBsAg negative
   5.   HBV DNA positive, HBV core protein IgM negative, HBsAg positive
4. Which of the following neonates should receive hepatitis B immune globulin within 12 hours after birth?
   1.   A 38 weeks’ gestation neonate (birth weight 3600 g) whose mother is hepatitis B surface antigen (HBsAg)
      negative
   2.   A 39 weeks’ gestation neonate (birth weight 3750 g) whose mother has HBsAg serology that is unknown,
      but will be confirmed within 24 hours after delivery
   3.   A 37 weeks’ gestation neonate (birth weight 3550 g) whose mother is positive for hepatitis C antibody
      only
   4.   A 34 weeks’ gestation neonate (birth weight 2500 g) whose mother is HBsAg negative but developed
      chorioamnionitis in labor
   5.   A 36 weeks’ gestation neonate (birth weight 1850 g) whose mother has HBsAg serology that cannot be resulted until 36 hours after delivery
5. Autoimmune hepatitis is a clinical diagnosis based on certain diagnostic criteria; no single test will make this diagnosis. Important positive features include the following
   EXCEPT
   1.   Female gender
   2.   Elevation in alkaline phosphatase
   3.   Elevated y-globulin levels
   4.   Presence of autoantibodies
   5.   Characteristic histologic findings