Most common complication of prostaglandin 1: Apnea.
Please remember, elevated prostaglandin levels can cause hypertrophic pyloric stenosis. For patients who develop apnea, endotracheal intubation is indicated.
A newborn received prostaglandin therapy for 5 days. The newborn developed non-bilious vomiting. Most likely diagnosis:
hypertrophic pyloric stenosis secondary to prostaglandin.
Management: Discontinue prostaglandin.
The vomiting stops and pyloric stenosis resolves slowly with the discontinuation of medication.
The child should be operated for the underlying cardiac condition.
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