How to detect Salmonella enteric carrier:
1. Positive stool culture, because such patients excrete a lot of Salmonella in stool. Sometimes urine culture may be positive.
2. If negative stool culture, then do duodenal aspirate culture to find out about biliary excretion of Salmonella or culture of duodenal string capsule, which should not be performed in very young or very ill children.
How to treat chronic carrier:
1. High dose of ampicillin (or amoxicillin) plus probenecid or trimethoprim -sulfamethoxazole for 4-6 week.
2. Patients with cholelithiasis or cholecystitis: cholecystectomy within 14 days of antibiotic therapy.
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