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Monday, October 28, 2019

PEDIATRIC HEPATOLOGY MCQS: ANSWER TO MCQ 04

Answer 4 A

Autoimmune hepatitis responds very well to steroid therapy. The recommended initial therapy for AIH is 2 mg/kg/day of prednisone. Once transaminases are below 100, prednisone can be weaned to low dose. Once bilirubin levels have normalized, azathioprine may be started as maintenance therapy, preferably in concert with low-dose steroids to prevent initial relapse.
In patients who are intolerant of both corticosteroids and azathioprine, cyclosporine, tacrolimus, or mycophenolate may be considered.

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