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Friday, April 5, 2019

Hyperosmolar non-ketotic coma


Criteria to diagnose Hyperosmolar non-ketotic coma (Hyperglycemic hyperosmolar state; HHS)
  1. Plasma glucose concentration >33.3 mmol/L (600 mg/dL)
  2. Arterial pH >7.30
  3. Serum bicarbonate >15 mmol/L
  4. Small ketonuria, absent to mild ketonemia
  5. Effective serum osmolality >320 mOsm/kg
  6. Clinically : Stupor or coma, severe dehydration


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